A database of hormones and their receptors |
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HMRbase accession number | 10013 |
Swiss-prot Accession number | P01176 (Sequence in FASTA format) |
Description | Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin(Ocytocin); Neurophysin 1] (Fragment). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the vasopressin/oxytocin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland |
Protein Length | 105 Amino acids |
Molecular weight | 10723 |
References | 1 PubMed abstract 13629241 2 PubMed abstract 10343920 3 PubMed abstract 7271775 |
Domain Name | Hormone_5 |
Hormone Name | Oxytocin |
Mature Hormone Sequence | CYIQNCPLG |
Position of mature hormone in Pre-Hormone protein | 9 Residues from position (1-9) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10029 |
Swiss-prot Accession number | P01226 (Sequence in FASTA format) |
Description | Follitropin subunit beta precursor (Follicle-stimulating hormone betasubunit) (FSH-beta) (FSH-B) (Follitropin beta chain). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates development of follicle and spermatogenesis in the reproductive organs |
Protein Length | 129 Amino acids |
Molecular weight | 14387 |
References | 1 PubMed abstract 11717129 2 PubMed abstract 670202 3 PubMed abstract 11717129 4 PubMed abstract 670202 |
Domain Name | Cys_knot |
Hormone Name | Follicle-stimulating hormone beta subunit |
Mature Hormone Sequence | NSCELTNITIAVEKEECGFCISINTTWCAGYCYTRDLVYKDPARPNIQKTCTFKELVYETVKVPGCAHHADSLYTYPVATACHCGKCNSDSTDCTVRGLGPSYCSFGDMKE |
Position of mature hormone in Pre-Hormone protein | 111 Residues from position (19-129) |
Receptor | P47799
Detail in HMRbase |
Gene ID | 100033829 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 10057 |
Swiss-prot Accession number | Q27IM2 (Sequence in FASTA format) |
Description | Parathyroid hormone precursor (Parathyrin) (PTH). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the parathyroid hormone family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion |
Protein Length | 115 Amino acids |
Molecular weight | 13062 |
References | 1 Rourke K.M., Kohn C.W., Rosol T.J., Toribio R.E.; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2 Shiue Y.-L., Caetano A.R., Lyons L.A., O'Brien S.J., Laughlin T.F.,Murray J.D., Bowling A.T.; Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. |
Domain Name | Parathyroid |
Hormone Name | Parathyroid hormone (Parathyrin) (PTH) |
Mature Hormone Sequence | SVSEIQLMHNLGKHLNSVERVEWLRKKLQDVHNFIALGAPIFHRDGGSQRPRKKEDNVLIESHQKSLGEADKADVDVLSKTKSQ |
Position of mature hormone in Pre-Hormone protein | 84 Residues from position (32-115) |
Receptor | N/A |
Gene ID | 100034104 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10166 |
Swiss-prot Accession number | Q28376 (Sequence in FASTA format) |
Description | Thyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Indispensable for the control of thyroid structure and metabolism |
Protein Length | 138 Amino acids |
Molecular weight | 15663 |
References | 1 Kania S.A., Olchowy T.W., Frank L.A.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
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Domain Name | Cys_knot |
Hormone Name | Thyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain) |
Mature Hormone Sequence | FCIPTEYMMHVERKECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFMYKTVEIPGCPDHVTPYFSYPVAVSCKCGKCNTDYSDCIHEAIKANYCTKPQKSY |
Position of mature hormone in Pre-Hormone protein | 112 Residues from position (21-132) |
Receptor | N/A |
Gene ID | 100034188 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10231 |
Swiss-prot Accession number | Q9N0V5 (Sequence in FASTA format) |
Description | Calcitonin precursor. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the calcitonin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones |
Protein Length | 140 Amino acids |
Molecular weight | 15358 |
References | 1 PubMed abstract 12581884 |
Domain Name | Calc_CGRP_IAPP |
Hormone Name | Calcitonin |
Mature Hormone Sequence | CSNLSTCVLGTYTQDLNKFHTFPQTAIGVGAP |
Position of mature hormone in Pre-Hormone protein | 32 Residues from position (84-115) |
Receptor | N/A |
Gene ID | 100033906 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10639 |
Swiss-prot Accession number | P08751 (Sequence in FASTA format) |
Description | Lutropin/choriogonadotropin subunit beta precursor (LSH-B/CG-B)(Luteinizing hormone subunit beta) (Lutropin/choriogonadotropin betachain). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit beta family. |
Tissue Specificity | N/A |
Post translational modification | Microheterogeneity at Asn-33. O-glycosylation appears to be responsible for the beta subunit contribution to the difference in LH-receptor binding activity between LSH-B and CG-B. |
Function | Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids |
Protein Length | 169 Amino acids |
Molecular weight | 17865 |
References | 1 PubMed abstract 1379674 2 PubMed abstract 3298239 3 PubMed abstract 3298238 4 Ward D.N., Moore W.T. Jr., Burleigh B.D.; "Structural studies on equine chorionic gonadotropin."; J. Protein Chem. 1:263-280(1982). 5 PubMed abstract 2331995 6 PubMed abstract 11133668 |
Domain Name | Cys_knot |
Hormone Name | Luteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta) |
Mature Hormone Sequence | SRGPLRPLCRPINATLAAEKEACPICITFTTSICAGYCPSMVRVMPAALPAIPQPVCTYRELRFASIRLPGCPPGVDPMVSFPVALSCHCGPCQIKTTDCGVFRDQPLACAPQASSSSKDPPSQPLTSTSTPTPGASRRSSHPLPIKTS |
Position of mature hormone in Pre-Hormone protein | 149 Residues from position (21-169) |
Receptor | N/A |
Gene ID | 100054774 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10739 |
Swiss-prot Accession number | P01245 (Sequence in FASTA format) |
Description | Somatotropin precursor (Growth hormone). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues |
Protein Length | 216 Amino acids |
Molecular weight | 24423 |
References | 1 PubMed abstract 8206392 2 PubMed abstract 965151 3 PubMed abstract 4747849 4 PubMed abstract 11946725 5 PubMed abstract 4876100 |
Domain Name | Hormone_1 |
Hormone Name | Growth hormone (Somatotropin) (GH) |
Mature Hormone Sequence | FPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDMELLRFSLLLIQSWLGPVQLLSRVFTNSLVFGTSDRVYEKLRDLEEGIQALMRELEDGSPRAGQILKQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF |
Position of mature hormone in Pre-Hormone protein | 190 Residues from position (27-216) |
Receptor | N/A |
Gene ID | 100034180 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10840 |
Swiss-prot Accession number | P01310 (Sequence in FASTA format) |
Description | Insulin precursor [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 86 Amino acids |
Molecular weight | 9147 |
References | 1 PubMed abstract 13373434 2 PubMed abstract 4640931 |
Domain Name | Insulin |
Hormone Name | Insulin B chain |
Mature Hormone Sequence | FVNQHLCGSHLVEALYLVCGERGFFYTPKA |
Position of mature hormone in Pre-Hormone protein | 30 Residues from position (1-30) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10841 |
Swiss-prot Accession number | P01310 (Sequence in FASTA format) |
Description | Insulin precursor [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 86 Amino acids |
Molecular weight | 9147 |
References | 1 PubMed abstract 13373434 2 PubMed abstract 4640931 |
Domain Name | Insulin |
Hormone Name | Insulin A chain |
Mature Hormone Sequence | GIVEQCCTGICSLYQLENYCN |
Position of mature hormone in Pre-Hormone protein | 21 Residues from position (66-86) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11014 |
Swiss-prot Accession number | P12420 (Sequence in FASTA format) |
Description | Prolactin precursor (PRL). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Prolactin acts primarily on the mammary gland by promoting lactation |
Protein Length | 229 Amino acids |
Molecular weight | 26256 |
References | 1 PubMed abstract 12742553 2 PubMed abstract 3045032 |
Domain Name | Hormone_1 |
Hormone Name | Prolactin |
Mature Hormone Sequence | LPICPSGAVNCQVSLRELFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFVTKAINSCHTSSLSTPEDKEQAQQIHHEDLLNLILRVLRSWNDPLYHLVSEVRGMQEAPEAILSKAIEIEEQNRRLLEGMEKIVGQVQPRIKENEVYSVWSGLPSLQMADEDSRLFAFYNLLHCLRRDSHKIDNYLKLLKCRIVYDSNC |
Position of mature hormone in Pre-Hormone protein | 199 Residues from position (31-229) |
Receptor | N/A |
Gene ID | 100034034 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11047 |
Swiss-prot Accession number | P63314 (Sequence in FASTA format) |
Description | Thymosin beta-10. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Cytoplasm |
Developmental Stage | N/A |
Similarity | Belongs to the thymosin beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization |
Protein Length | 44 Amino acids |
Molecular weight | 5026 |
References | 1 Takafuji V.A., Sharova L.V., Crisman M.V., Howard R.D.; "Equus caballus thymosin, beta 10 (TMSB10) mRNA."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
2 Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993). |
Domain Name | Thymosin |
Hormone Name | Thymosin beta-10 |
Mature Hormone Sequence | ADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS |
Position of mature hormone in Pre-Hormone protein | 43 Residues from position (2-44) |
Receptor | N/A |
Gene ID | 100033928 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11057 |
Swiss-prot Accession number | P62327 (Sequence in FASTA format) |
Description | Thymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Cytoplasm |
Developmental Stage | N/A |
Similarity | Belongs to the thymosin beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization |
Protein Length | 44 Amino acids |
Molecular weight | 5053 |
References | 1 Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2 Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. |
Domain Name | Thymosin |
Hormone Name | Thymosin beta-4 |
Mature Hormone Sequence | SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES |
Position of mature hormone in Pre-Hormone protein | 43 Residues from position (2-44) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11058 |
Swiss-prot Accession number | P62327 (Sequence in FASTA format) |
Description | Thymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Cytoplasm |
Developmental Stage | N/A |
Similarity | Belongs to the thymosin beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase |
Protein Length | 44 Amino acids |
Molecular weight | 5053 |
References | 1 Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2 Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. |
Domain Name | Thymosin |
Hormone Name | Hematopoietic system regulatory peptide |
Mature Hormone Sequence | SDKP |
Position of mature hormone in Pre-Hormone protein | 4 Residues from position (2-5) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11150 |
Swiss-prot Accession number | P55885 (Sequence in FASTA format) |
Description | Gastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the gastrin/cholecystokinin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine |
Protein Length | 107 Amino acids |
Molecular weight | 11884 |
References | 1 PubMed abstract 9716385 |
Domain Name | Gastrin |
Hormone Name | Big gastrin |
Mature Hormone Sequence | QLGLQGSPHLVADLSKKQGPWLEKEEAAYGWMDF |
Position of mature hormone in Pre-Hormone protein | 34 Residues from position (62-95) |
Receptor | N/A |
Gene ID | 100034214 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11151 |
Swiss-prot Accession number | P55885 (Sequence in FASTA format) |
Description | Gastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the gastrin/cholecystokinin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine |
Protein Length | 107 Amino acids |
Molecular weight | 11884 |
References | 1 PubMed abstract 9716385 |
Domain Name | Gastrin |
Hormone Name | Gastrin |
Mature Hormone Sequence | QGPWLEKEEAAYGWMDF |
Position of mature hormone in Pre-Hormone protein | 17 Residues from position (79-95) |
Receptor | N/A |
Gene ID | 100034214 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11217 |
Swiss-prot Accession number | P22969 (Sequence in FASTA format) |
Description | Prorelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals |
Protein Length | 182 Amino acids |
Molecular weight | 20721 |
References | 1 Min K., Shiota K., Ogawa T.; "Molecular cloning of equine preprorelaxin cDNA."; J. Reprod. Dev. 42:171-178(1996).
2 PubMed abstract 7543295 3 PubMed abstract 2055195 |
Domain Name | Insulin |
Hormone Name | Relaxin B chain |
Mature Hormone Sequence | QKPDDVIKACGRELARLRIEICGSLSWK |
Position of mature hormone in Pre-Hormone protein | 28 Residues from position (26-53) |
Receptor | N/A |
Gene ID | 100033823 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11218 |
Swiss-prot Accession number | P22969 (Sequence in FASTA format) |
Description | Prorelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain]. |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals |
Protein Length | 182 Amino acids |
Molecular weight | 20721 |
References | 1 Min K., Shiota K., Ogawa T.; "Molecular cloning of equine preprorelaxin cDNA."; J. Reprod. Dev. 42:171-178(1996).
2 PubMed abstract 7543295 3 PubMed abstract 2055195 |
Domain Name | Insulin |
Hormone Name | Relaxin A chain |
Mature Hormone Sequence | QLSHKCCYWGCTRKELARQC |
Position of mature hormone in Pre-Hormone protein | 20 Residues from position (163-182) |
Receptor | N/A |
Gene ID | 100033823 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11304 |
Swiss-prot Accession number | P01220 (Sequence in FASTA format) |
Description | Glycoprotein hormones alpha chain precursor (Anterior pituitaryglycoprotein hormones common subunit alpha) (Follitropin alpha chain)(Follicle-stimulating hormone alpha chain) (FSH-alpha) (Lutropin alphachain) (Luteinizing hormone alpha chain) (LSH-alpha) (Thyrotropinalpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit alpha family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 120 Amino acids |
Molecular weight | 13809 |
References | 1 Min K., Shinozaki M., Miyazawa K., Nishimura R., Sasaki N., Shiota K.,Ogawa T.; "Nucleotide sequence of eCG alpha-subunit cDNA and its expression inthe equine placenta."; J. Reprod. Dev. 40:301-305(1994).
2 PubMed abstract 3437252 3 Moore W.T. Jr., Ward D.N., Burleigh B.D.; "Primary structure of pregnant mare serum gonadotropin alphasubunit."; Fed. Proc. 38:462-462(1979). 4 PubMed abstract 670201 5 Min K., Shinozaki M., Miyazawa K., Nishimura R., Sasaki N., Shiota K.,Ogawa T.; "Nucleotide sequence of eCG alpha-subunit cDNA and its expression inthe equine placenta."; J. Reprod. Dev. 40:301-305(1994). 6 PubMed abstract 3437252 7 Moore W.T. Jr., Ward D.N., Burleigh B.D.; "Primary structure of pregnant mare serum gonadotropin alphasubunit."; Fed. Proc. 38:462-462(1979). 8 PubMed abstract 670201 |
Domain Name | Hormone_6 |
Hormone Name | Glycoprotein hormones alpha chain |
Mature Hormone Sequence | FPDGEFTTQDCPECKLRENKYFFKLGVPIYQCKGCCFSRAYPTPARSRKTMLVPKNITSESTCCVAKAFIRVTVMGNIKLENHTQCYCSTCYHHKI |
Position of mature hormone in Pre-Hormone protein | 96 Residues from position (25-120) |
Receptor | P47799
Detail in HMRbase |
Gene ID | 100034174 |
PDB ID | N/A |
Drugpedia | wiki |
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