A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10013
Swiss-prot Accession numberP01176 (Sequence in FASTA format)
DescriptionOxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin(Ocytocin); Neurophysin 1] (Fragment).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the vasopressin/oxytocin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland
Protein Length105 Amino acids
Molecular weight10723
References1  PubMed abstract 13629241
2  PubMed abstract 10343920
3  PubMed abstract 7271775
Domain NameHormone_5  
Hormone NameOxytocin
Mature Hormone SequenceCYIQNCPLG
Position of mature hormone in Pre-Hormone protein9 Residues from position (1-9)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10029
Swiss-prot Accession numberP01226 (Sequence in FASTA format)
DescriptionFollitropin subunit beta precursor (Follicle-stimulating hormone betasubunit) (FSH-beta) (FSH-B) (Follitropin beta chain).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStimulates development of follicle and spermatogenesis in the reproductive organs
Protein Length129 Amino acids
Molecular weight14387
References1  PubMed abstract 11717129
2  PubMed abstract 670202
3  PubMed abstract 11717129
4  PubMed abstract 670202
Domain NameCys_knot  
Hormone NameFollicle-stimulating hormone beta subunit
Mature Hormone SequenceNSCELTNITIAVEKEECGFCISINTTWCAGYCYTRDLVYKDPARPNIQKTCTFKELVYETVKVPGCAHHADSLYTYPVATACHCGKCNSDSTDCTVRGLGPSYCSFGDMKE
Position of mature hormone in Pre-Hormone protein111 Residues from position (19-129)
ReceptorP47799    Detail in HMRbase   
Gene ID100033829      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 3

HMRbase accession number10057
Swiss-prot Accession numberQ27IM2 (Sequence in FASTA format)
DescriptionParathyroid hormone precursor (Parathyrin) (PTH).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the parathyroid hormone family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion
Protein Length115 Amino acids
Molecular weight13062
References1   Rourke K.M., Kohn C.W., Rosol T.J., Toribio R.E.; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2   Shiue Y.-L., Caetano A.R., Lyons L.A., O'Brien S.J., Laughlin T.F.,Murray J.D., Bowling A.T.; Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Domain NameParathyroid  
Hormone NameParathyroid hormone (Parathyrin) (PTH)
Mature Hormone SequenceSVSEIQLMHNLGKHLNSVERVEWLRKKLQDVHNFIALGAPIFHRDGGSQRPRKKEDNVLIESHQKSLGEADKADVDVLSKTKSQ
Position of mature hormone in Pre-Hormone protein84 Residues from position (32-115)
ReceptorN/A
Gene ID100034104      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10166
Swiss-prot Accession numberQ28376 (Sequence in FASTA format)
DescriptionThyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionIndispensable for the control of thyroid structure and metabolism
Protein Length138 Amino acids
Molecular weight15663
References1   Kania S.A., Olchowy T.W., Frank L.A.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
Domain NameCys_knot  
Hormone NameThyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain)
Mature Hormone SequenceFCIPTEYMMHVERKECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFMYKTVEIPGCPDHVTPYFSYPVAVSCKCGKCNTDYSDCIHEAIKANYCTKPQKSY
Position of mature hormone in Pre-Hormone protein112 Residues from position (21-132)
ReceptorN/A
Gene ID100034188      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10231
Swiss-prot Accession numberQ9N0V5 (Sequence in FASTA format)
DescriptionCalcitonin precursor.
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the calcitonin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionCauses a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones
Protein Length140 Amino acids
Molecular weight15358
References1  PubMed abstract 12581884
Domain NameCalc_CGRP_IAPP  
Hormone NameCalcitonin
Mature Hormone SequenceCSNLSTCVLGTYTQDLNKFHTFPQTAIGVGAP
Position of mature hormone in Pre-Hormone protein32 Residues from position (84-115)
ReceptorN/A
Gene ID100033906      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10639
Swiss-prot Accession numberP08751 (Sequence in FASTA format)
DescriptionLutropin/choriogonadotropin subunit beta precursor (LSH-B/CG-B)(Luteinizing hormone subunit beta) (Lutropin/choriogonadotropin betachain).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification Microheterogeneity at Asn-33. O-glycosylation appears to be responsible for the beta subunit contribution to the difference in LH-receptor binding activity between LSH-B and CG-B.
FunctionPromotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids
Protein Length169 Amino acids
Molecular weight17865
References1  PubMed abstract 1379674
2  PubMed abstract 3298239
3  PubMed abstract 3298238
4   Ward D.N., Moore W.T. Jr., Burleigh B.D.; "Structural studies on equine chorionic gonadotropin."; J. Protein Chem. 1:263-280(1982).
5  PubMed abstract 2331995
6  PubMed abstract 11133668
Domain NameCys_knot  
Hormone NameLuteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
Mature Hormone SequenceSRGPLRPLCRPINATLAAEKEACPICITFTTSICAGYCPSMVRVMPAALPAIPQPVCTYRELRFASIRLPGCPPGVDPMVSFPVALSCHCGPCQIKTTDCGVFRDQPLACAPQASSSSKDPPSQPLTSTSTPTPGASRRSSHPLPIKTS
Position of mature hormone in Pre-Hormone protein149 Residues from position (21-169)
ReceptorN/A
Gene ID100054774      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10739
Swiss-prot Accession numberP01245 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length216 Amino acids
Molecular weight24423
References1  PubMed abstract 8206392
2  PubMed abstract 965151
3  PubMed abstract 4747849
4  PubMed abstract 11946725
5  PubMed abstract 4876100
Domain NameHormone_1  
Hormone NameGrowth hormone (Somatotropin) (GH)
Mature Hormone SequenceFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDMELLRFSLLLIQSWLGPVQLLSRVFTNSLVFGTSDRVYEKLRDLEEGIQALMRELEDGSPRAGQILKQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
Position of mature hormone in Pre-Hormone protein190 Residues from position (27-216)
ReceptorN/A
Gene ID100034180      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10840
Swiss-prot Accession numberP01310 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length86 Amino acids
Molecular weight9147
References1  PubMed abstract 13373434
2  PubMed abstract 4640931
Domain NameInsulin  
Hormone NameInsulin B chain
Mature Hormone SequenceFVNQHLCGSHLVEALYLVCGERGFFYTPKA
Position of mature hormone in Pre-Hormone protein30 Residues from position (1-30)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10841
Swiss-prot Accession numberP01310 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length86 Amino acids
Molecular weight9147
References1  PubMed abstract 13373434
2  PubMed abstract 4640931
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTGICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (66-86)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number11014
Swiss-prot Accession numberP12420 (Sequence in FASTA format)
DescriptionProlactin precursor (PRL).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionProlactin acts primarily on the mammary gland by promoting lactation
Protein Length229 Amino acids
Molecular weight26256
References1  PubMed abstract 12742553
2  PubMed abstract 3045032
Domain NameHormone_1  
Hormone NameProlactin
Mature Hormone SequenceLPICPSGAVNCQVSLRELFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFVTKAINSCHTSSLSTPEDKEQAQQIHHEDLLNLILRVLRSWNDPLYHLVSEVRGMQEAPEAILSKAIEIEEQNRRLLEGMEKIVGQVQPRIKENEVYSVWSGLPSLQMADEDSRLFAFYNLLHCLRRDSHKIDNYLKLLKCRIVYDSNC
Position of mature hormone in Pre-Hormone protein199 Residues from position (31-229)
ReceptorN/A
Gene ID100034034      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number11047
Swiss-prot Accession numberP63314 (Sequence in FASTA format)
DescriptionThymosin beta-10.
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5026
References1   Takafuji V.A., Sharova L.V., Crisman M.V., Howard R.D.; "Equus caballus thymosin, beta 10 (TMSB10) mRNA."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
2   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID100033928      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number11057
Swiss-prot Accession numberP62327 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2   Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number11058
Swiss-prot Accession numberP62327 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2   Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number11150
Swiss-prot Accession numberP55885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length107 Amino acids
Molecular weight11884
References1  PubMed abstract 9716385
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGSPHLVADLSKKQGPWLEKEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (62-95)
ReceptorN/A
Gene ID100034214      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number11151
Swiss-prot Accession numberP55885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length107 Amino acids
Molecular weight11884
References1  PubMed abstract 9716385
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEKEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (79-95)
ReceptorN/A
Gene ID100034214      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11217
Swiss-prot Accession numberP22969 (Sequence in FASTA format)
DescriptionProrelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals
Protein Length182 Amino acids
Molecular weight20721
References1   Min K., Shiota K., Ogawa T.; "Molecular cloning of equine preprorelaxin cDNA."; J. Reprod. Dev. 42:171-178(1996).
2  PubMed abstract 7543295
3  PubMed abstract 2055195
Domain NameInsulin  
Hormone NameRelaxin B chain
Mature Hormone SequenceQKPDDVIKACGRELARLRIEICGSLSWK
Position of mature hormone in Pre-Hormone protein28 Residues from position (26-53)
ReceptorN/A
Gene ID100033823      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number11218
Swiss-prot Accession numberP22969 (Sequence in FASTA format)
DescriptionProrelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals
Protein Length182 Amino acids
Molecular weight20721
References1   Min K., Shiota K., Ogawa T.; "Molecular cloning of equine preprorelaxin cDNA."; J. Reprod. Dev. 42:171-178(1996).
2  PubMed abstract 7543295
3  PubMed abstract 2055195
Domain NameInsulin  
Hormone NameRelaxin A chain
Mature Hormone SequenceQLSHKCCYWGCTRKELARQC
Position of mature hormone in Pre-Hormone protein20 Residues from position (163-182)
ReceptorN/A
Gene ID100033823      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number11304
Swiss-prot Accession numberP01220 (Sequence in FASTA format)
DescriptionGlycoprotein hormones alpha chain precursor (Anterior pituitaryglycoprotein hormones common subunit alpha) (Follitropin alpha chain)(Follicle-stimulating hormone alpha chain) (FSH-alpha) (Lutropin alphachain) (Luteinizing hormone alpha chain) (LSH-alpha) (Thyrotropinalpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha).
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length120 Amino acids
Molecular weight13809
References1   Min K., Shinozaki M., Miyazawa K., Nishimura R., Sasaki N., Shiota K.,Ogawa T.; "Nucleotide sequence of eCG alpha-subunit cDNA and its expression inthe equine placenta."; J. Reprod. Dev. 40:301-305(1994).
2  PubMed abstract 3437252
3   Moore W.T. Jr., Ward D.N., Burleigh B.D.; "Primary structure of pregnant mare serum gonadotropin alphasubunit."; Fed. Proc. 38:462-462(1979).
4  PubMed abstract 670201
5   Min K., Shinozaki M., Miyazawa K., Nishimura R., Sasaki N., Shiota K.,Ogawa T.; "Nucleotide sequence of eCG alpha-subunit cDNA and its expression inthe equine placenta."; J. Reprod. Dev. 40:301-305(1994).
6  PubMed abstract 3437252
7   Moore W.T. Jr., Ward D.N., Burleigh B.D.; "Primary structure of pregnant mare serum gonadotropin alphasubunit."; Fed. Proc. 38:462-462(1979).
8  PubMed abstract 670201
Domain NameHormone_6  
Hormone NameGlycoprotein hormones alpha chain
Mature Hormone SequenceFPDGEFTTQDCPECKLRENKYFFKLGVPIYQCKGCCFSRAYPTPARSRKTMLVPKNITSESTCCVAKAFIRVTVMGNIKLENHTQCYCSTCYHHKI
Position of mature hormone in Pre-Hormone protein96 Residues from position (25-120)
ReceptorP47799    Detail in HMRbase   
Gene ID100034174      
PDB IDN/A
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